"The Global South and/in the Global North: Interdisciplinary Investigations"This special issue of The Global South encourages power-conscious readings of place that challenge nation-based models of the Global North (First World) and the Global South (Third World) by suggesting that one may exist within the other. The political clout of a nation, its fiscal soundness or disrepair, the availability of education and the accessibility of health care, obviously do not consistently characterize the experiences of all of its residents, and this issue explores that gap. We sought out essays that focus on blurring political demarcations of space, as well as those that transgress disciplinary lines. Questions guiding our thinking and the issue’s theme include these: where do we find evidence of the Global South within the Global North, particularly within countries resolutely classified as First World? Might we find the Global North similarly pocketed into the Global South? What might be gained by revamping traditional nation-based classifications of how power is allotted? Beyond disallowing grand narratives by insisting on individual agency, what are the pragmatic advantages to reading place in a granular way? In other words, what might be revealed by situating seemingly disparate locations along a spectrum that accounts for the distribution of power as fundamentally connected to the characteristics of individualized spaces? What case studies most clearly illustrate the complications in traditional Global South/Global North hierarchies? And finally, how is interdisciplinary study particularly well-suited to grapple with the exigencies of place-based analysis?